Open AccessNeuron-specific enolase correlates to laboratory markers of haemolysis in patients on long-term circulatory support†
Author(s) -
Ulrich Geisen,
Christoph Benk,
Friedhelm Beyersdorf,
Rolf Klemm,
Georg Trummer,
Beatrice Özbek,
F. Kern,
Claudia Heilmann
Publication year - 2015
Publication title -
european journal of cardio-thoracic surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.303
H-Index - 133
eISSN - 1873-734X
pISSN - 1010-7940
DOI - 10.1093/ejcts/ezu513
Subject(s) - haemolysis , enolase , haptoglobin , lactate dehydrogenase , hematocrit , medicine , circulatory system , hemolysis , pathology , gastroenterology , biology , immunology , biochemistry , immunohistochemistry , enzyme
Neuron-specific enolase (NSE) is used as a diagnostic tool in neuropathies, cerebral diseases or traumata and for some tumours. Furthermore, it is also expressed by erythrocytes and platelets and has been linked to haemolysis ex vivo as a laboratory issue. Chronic haemolysis is frequently associated with mechanical circulatory support by ventricular assist device (VAD) or total artificial heart (TAH). Therefore, we compared NSE with indicators of haemolysis in VAD and TAH patients.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom