Open AccessImpact of the epidermal growth factor receptor mutation status on the post-recurrence survival of patients with surgically resected non-small-cell lung cancer
Author(s) -
Tomoyoshi Takenaka,
Mitsuhiro Takenoyama,
Masafumi Yamaguchi,
Ryo Toyozawa,
Eiko Inamasu,
Miyako Kojo,
Gouji Toyokawa,
Tsukihisa Yoshida,
Yoshimasa Shiraishi,
Yosuke Morodomi,
Fumihiko Hirai,
Kenichi Taguchi,
Mototsugu Shimokawa,
Takashi Seto,
Yukito Ichinose
Publication year - 2014
Publication title -
european journal of cardio-thoracic surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.303
H-Index - 133
eISSN - 1873-734X
pISSN - 1010-7940
DOI - 10.1093/ejcts/ezu227
Subject(s) - medicine , epidermal growth factor receptor , lung cancer , oncology , multivariate analysis , epidermal growth factor , targeted therapy , cancer , receptor
The impact of epidermal growth factor receptor (EGFR) status and the use of EGFR-tyrosine kinase inhibitor (EGFR-TKI) therapy have not been well discussed only in recurrent non-small-cell lung cancer (NSCLC). The purpose of this study was to identify the prognostic factors associated with post-recurrence survival after surgical resection of NSCLC in terms of the EGFR mutation status and the use of EGFR-TKI therapy.
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