Open AccessA microthymoma and no germinal centre in myasthenia gravis
Author(s) -
Masatsugu Hamaji,
Paul A. VanderLaan,
David J. Sugarbaker,
C J McNamee
Publication year - 2013
Publication title -
european journal of cardio-thoracic surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.303
H-Index - 133
eISSN - 1873-734X
pISSN - 1010-7940
DOI - 10.1093/ejcts/ezt208
Subject(s) - myasthenia gravis , thymectomy , thymoma , germinal center , pathological , hyperplasia , medicine , pathology , cardiothoracic surgery , thoracotomy , computed tomography , radiology , surgery , immunology , antibody , b cell
A 43-year-old woman with a 1-year history of generalized myasthenia gravis was referred for a video-assisted thorascopic surgery thymectomy. The preoperative chest computed tomography revealed mild diffuse thymic hyperplasia. Pathology of the resected thymus gland revealed a 6-mm World Health Organization (WHO) Type AB microthymoma without thymic germinal centres. The entity of microthymoma was reviewed with a focus on examining the pathological and therapeutic differences between thymic hyperplasia and microscopic thymoma.
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