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Changes in pulmonary function tests predict radiological response to chemotherapy in malignant pleural mesothelioma†
Author(s) -
Giuseppe Marulli,
Francesco Chiara,
Fausto Braccioni,
Egle Perissinotto,
Giulia Pasello,
Adolfo Favaretto,
Cristiano Breda,
Federico Rea
Publication year - 2013
Publication title -
european journal of cardio-thoracic surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.303
H-Index - 133
eISSN - 1873-734X
pISSN - 1010-7940
DOI - 10.1093/ejcts/ezs624
Subject(s) - mesothelioma , radiological weapon , medicine , chemotherapy , pulmonary function testing , oncology , radiology , pathology
Response to chemotherapy in malignant pleural mesothelioma (MPM) is usually evaluated by radiological criteria, but no common agreement exists on their validity, yet. The cytoreductive effect of chemotherapy on pleural thickening may make the lung more expansible, reducing the restrictive ventilatory impairment. The aim of this study was to evaluate the changes in pulmonary function following chemotherapy in patients with MPM and to correlate these findings with radiological changes.

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