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Crohn's disease [CD] arises through host-environment interaction. Abnormal gene expression results from disturbed pathway activation or response to bacteria. We aimed to determine activated pathways and driving cell types in paediatric CD.

journal of crohn's and colitis

Ileal Transcriptomic Analysis in Paediatric Crohn’s Disease Reveals<i>IL17-</i>and<i>NOD-</i>signalling Expression Signatures in Treatment-naïve Patients and Identifies Epithelial Cells Driving Differentially Expressed Genes

Ileal Transcriptomic Analysis in Paediatric Crohn’s Disease RevealsIL17-andNOD-signalling Expression Signatures in Treatment-naïve Patients and Identifies Epithelial Cells Driving Differentially Expressed Genes