Open AccessHuman adipose mesenchymal stem cells overexpressing dual chemotactic gene showed enhanced angiogenic capacity in ischaemic hindlimb model
Author(s) -
Younggeul Min,
Seong-Ho Han,
Hyun Aae Ryu,
SungWhan Kim
Publication year - 2018
Publication title -
cardiovascular research
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 2.774
H-Index - 219
eISSN - 1755-3245
pISSN - 0008-6363
DOI - 10.1093/cvr/cvy086
Subject(s) - matrigel , mesenchymal stem cell , neovascularization , arteriogenesis , hindlimb , angiogenesis , vasculogenesis , adipose tissue , stem cell , biology , pathology , immunology , medicine , cancer research , microbiology and biotechnology , progenitor cell , anatomy , endocrinology
In present study, we sought to characterize the angio-vasculogenic property of human adipose mesenchymal stem cells (ASCs) overexpressing dual chemokine GCP-2 and SDF-1α (ASC-G/S) and to determine the therapeutic potential of ASC-G/S in the context of experimental ischaemia.
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