The role of pulsatile flow in controlling microvascular retinal endothelial and pericyte cell apoptosis and proliferation | Zendy

Tony E. Walshe | Zendy; Paul Connell | Zendy; Lorna M. Cryan | Zendy; Gail Ferguson | Zendy; Colm O’Brien | Zendy; Paul A. Cahill | Zendy

Open Access

The role of pulsatile flow in controlling microvascular retinal endothelial and pericyte cell apoptosis and proliferation

Author(s) -

Tony E. Walshe,

Paul Connell,

Lorna M. Cryan,

Gail Ferguson,

Colm O’Brien,

Paul A. Cahill

Publication year - 2010

Publication title -

cardiovascular research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.774

H-Index - 219

eISSN - 1755-3245

pISSN - 0008-6363

DOI - 10.1093/cvr/cvq341

Subject(s) - pulsatile flow , pericyte , apoptosis , biology , endothelial stem cell , endocrinology , medicine , endothelium , enos , nitric oxide , nitric oxide synthase , biochemistry , in vitro

Aberrant retinal blood flow is a hallmark of various retinopathies and may be a causative factor in the pathology associated with these conditions. We examined the effects of pulsatile flow on bovine retinal endothelial cell (BREC) and bovine retinal pericyte (BRP) apoptosis and proliferation.

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