Open AccessHuman cardiac and bone marrow stromal cells exhibit distinctive properties related to their origin
Author(s) -
Alessandra Rossini,
Caterina Frati,
Costanza Annamaria Lagrasta,
Gallia Graiani,
Alessandro Scopece,
Stefano Cavalli,
Ezio Musso,
Marco Baccarin,
Marina Di Segni,
Francesco Fagi,
Antonia Germani,
Eugenio Quaini,
Manuel Mayr,
Qingbo Xu,
Andrea Barbuti,
Dario DiFrancesco,
Giulio Pompilio,
Federico Quaini,
Carlo Gaetano,
Maurizio C. Capogrossi
Publication year - 2010
Publication title -
cardiovascular research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.774
H-Index - 219
eISSN - 1755-3245
pISSN - 0008-6363
DOI - 10.1093/cvr/cvq290
Subject(s) - stromal cell , mesenchymal stem cell , bone marrow , human bone , cardiac function curve , in vitro , transplantation , in vivo , cell , pathology , medicine , cancer research , microbiology and biotechnology , biology , heart failure , biochemistry
Bone marrow mesenchymal stromal cell (BMStC) transplantation into the infarcted heart improves left ventricular function and cardiac remodelling. However, it has been suggested that tissue-specific cells may be better for cardiac repair than cells from other sources. The objective of the present work has been the comparison of in vitro and in vivo properties of adult human cardiac stromal cells (CStC) to those of syngeneic BMStC.
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