Contribution of CXCR4+/PDGFRβ+ progenitor cells in hypoxic alveolar arterioles muscularization: role of myocardin
Author(s) -
Wei Jie,
Xiaoyan Wang,
Lei Huang,
Junli Guo,
Dong Kuang,
Pengcheng Zhu,
Mei Li,
Xia Zhao,
Yaqi Duan,
Guoping Wang,
Qilin Ao
Publication year - 2010
Publication title -
cardiovascular research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.774
H-Index - 219
eISSN - 1755-3245
pISSN - 0008-6363
DOI - 10.1093/cvr/cvq147
Subject(s) - progenitor cell , myocardin , microbiology and biotechnology , biology , bone marrow , stem cell , immunology , transcription factor , gene , biochemistry , serum response factor
Bone marrow (BM) progenitor cells may contribute to vascular remodelling. The present study aimed to investigate the contribution of BM-derived CXCR4(+) (a CXC chemokine receptor) and PDGFRbeta(+) (platelet-derived growth factor receptor beta) progenitor cells in hypoxia-induced muscularization of alveolar arterioles.
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