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This study investigated the mechanism of Na +  uptake in freshwater by the endangered pupfish,  Cyprinodon macularius. Cyprinodon macularius  exhibits a low-affinity uptake system and appears to be relatively inflexibile with respect to mechanisms of Na +  uptake compared with most freshwater species.

Characterization of Na+ uptake in the endangered desert pupfish, Cyprinodon macularius (Baird and Girard)