Open AccessSerum microRNAs are altered in various stages of chronic kidney disease: a preliminary study
Author(s) -
Benjamin Brigant,
Valérie MetzingerLe Meuth,
Ziad Massy,
Nathalie McKay,
Sophie Liabeuf,
Marion Pelletier,
Marion Sallée,
Eléonore M’Baya-Moutoula,
Pascale Paul,
Tilman B. Drüeke,
Stéphane Burtey,
Laurent Metzinger
Publication year - 2016
Publication title -
clinical kidney journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.033
H-Index - 40
eISSN - 2048-8513
pISSN - 2048-8505
DOI - 10.1093/ckj/sfw060
Subject(s) - microrna , kidney disease , medicine , renal function , pathophysiology , biomarker , hemodialysis , disease , case control study , immunology , oncology , biology , gene , biochemistry
MicroRNAs (miRNAs) are innovative and informative blood-based biomarkers involved in numerous pathophysiological processes. In this study and based on our previous experimental data, we investigated miR-126, miR-143, miR-145, miR-155 and miR-223 as potential circulating biomarkers for the diagnosis and prognosis of patients with chronic kidney disease (CKD). The primary objective of this study was to assess the levels of miRNA expression at various stages of CKD.
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