English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Zendy Open

Presents the pdf analysis as premium feature

PDF Analysis

Insights

Presents the summarisation as premium feature

Summarisation

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the zaia usage as premium feature

ZAIA

Zendy Tools

Zendy Plus

Presents the access of premium content as premium feature

Premium Content

The methoxy methyl phenylacetones share an isobaric relationship (equivalent mass but different elemental composition) to the controlled precursor substance 3,4-methylenedioxyphenylacetone. The 10 methoxy methyl phenylacetones as well as the methylenedioxyphenylacetones show essentially equivalent mass spectra with major fragment ions at  m/z  135 and 43. Those methoxy methyl phenylacetones with the methoxy group substituted ortho to the benzylic cation in the  m/z  135 ion show a further fragmentation to lose formaldehyde (CH 2 O) and yield a significant ion at  m/z  105. The loss of formaldehyde from the ortho methoxy benzyl cation was confirmed using commercially available regioisomeric 2-, 3-, and 4-methoxyphenylacetones. The 10 regioisomeric methoxy methyl phenylacetones were prepared from the appropriately substituted benzaldehydes. Complete gas chromatographic resolution of all ten regioisomeric ketones was obtained on a stationary phase containing modified β-cyclodextrin. Using the cyclodextrin containing phase, the ortho methoxysubstituted ketones (K1-K4) eluted before the meta-methoxysubstituted ketones (K5-K8) and the para-methoxy-substituted ketones (K9-K10) showed the greatest affinity for the stationary liquid phase and eluted last. Complete separation of the 10 ketones was not obtained on Rtx-1 and Rtx-200 columns.

Gas Chromatography-Mass Spectrometry Analysis of Regioisomeric Ring Substituted Methoxy Methyl Phenylacetones