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Acetylcholinesterase (AChE) is transiently expressed in several immature axon systems. Its presence in developing thalamocortical afferents has led to the use of enzyme histochemistry to visualize this axon system in rats. Because of the spatiotemporal distribution of the enzyme in the rat neocortex. it has been suggested that AChE plays a role in the establishment of thalamocortical connectivity.

Differential Expression of Acetylcholinesterase in the Developing Barrel Cortex of Three Rodent Species