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We identified two SNPs with potentials in risk-stratifying GS 7 prostate cancer patients and predicting reclassification among patients undergoing AS. It may have clinical implication in managing localized patients by optimizing patient selection and personalized monitoring prior to/during AS.

carcinogenesis

Genetic variants of the Wnt signaling pathway as predictors of aggressive disease and reclassification in men with early stage prostate cancer on active surveillance