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The lncRNAs play an important role in the occurrence and development of cancers. Here, we show that rs2147578 was significantly associated with increased risk for colorectal cancer in Chinese population and may exert its role by influencing the binding of lnc-LAMC2-1:1/miR-128-3p.

A functional polymorphism in lnc-LAMC2-1:1 confers risk of colorectal cancer by affecting miRNA binding