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E6-mediated PXN promotes colony formation and invasion via decreasing miR-218 expression in oral cancer cells. PXN expression may independently predict poor overall survival (OS) and relapse-free survival in oral cavity squamous cell carcinoma (OCSCC), especially in HPV-infected OCSCC.

Paxillin promotes tumor progression and predicts survival and relapse in oral cavity squamous cell carcinoma by microRNA-218 targeting