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H.pylori- associated catalase and SOD inhibit intercellular ROS-mediated signaling and thus protect transformed cells from apoptotic elimination.  H.pylori  antioxidant enzymes therefore have the potential to modulate an early step of oncogenesis through the regulation of survival of transformed cells.

Helicobacter pylori protects oncogenically transformed cells from reactive oxygen species-mediated intercellular induction of apoptosis