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We explored the mechanism of the AhR agonist, BNF, antitumor effects in human breast cancer cells and found that BNF inhibits breast cancer growth through the AKT pathway.

carcinogenesis

Beta-naphthoflavone (DB06732) mediates estrogen receptor-positive breast cancer cell cycle arrest through AhR-dependent regulation of PI3K/AKT and MAPK/ERK signaling