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1 Department of Neurology, Erasmus Medical Centre, 3015 CE Rotterdam, The Netherlands 2 Department of Internal Medicine, Erasmus Medical Centre, 3015 CE Rotterdam, The Netherlands 3 Department of Pathology, VU University Medical Centre, De Boelelaan 1117, 1081 HV Amsterdam, The Netherlands 4 Department of Clinical Genetics, Erasmus Medical Centre, 3015 CE Rotterdam, The Netherlands 5 DZNE, German Centre for Neurodegenerative Disease, 72076 Tübingen, Germany 6 Department of Neuropathology, University of Tübingen, 72076 Tübingen, Germany 7 Alzheimer Centre, Neuroscience Campus Amsterdam, 1007 MB Amsterdam, The Netherlands 8 Department of Neurology, Neuroscience Campus Amsterdam, 1007 MB Amsterdam, The Netherlands

Reply: PRKAR1B mutations are a rare cause of FUS negative neuronal intermediate filament inclusion disease