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Seizure is a recognised complication of Chronic Subdural Haematoma (CSDH). Blood Type A has been indicated as a risk factor for developing postoperative seizures in Acute Subdural Haematoma (ASDH). However, to our knowledge there has not been a similar study to see if there is an association between blood type and seizure risk in CSDH. Method 699 patients who had a CSDH surgically evacuated with burr holes between 2013 and 2019 were identified and their electronic and paper notes were retrospectively reviewed. Clinical information including their blood type and occurrence of postoperative seizure were recorded. Results 26/699 patients overall had a postoperative seizure (3.7%). Blood type A had a higher overall number of seizures (4.3%, 13/301) than other blood types (3.4%,13/379) however this difference was not statistically significant (p = 0.22). Conclusions There is no convincing evidence that patients with blood type A have a higher risk of seizures after CSDH than patients with other blood types. Therefore, there is no reason to manage patients with blood type A differently regarding seizure prophylaxis.

381 Is Risk of Postoperative Seizures Higher in Patients with Blood Type a in Chronic Subdural Haematoma?