English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Motivation: We introduce TRONCO (TRanslational ONCOlogy), an open-source Rpackage that implements the state-of-the-art algorithms for the inference ofcancer progression models from (epi)genomic mutational profiles. TRONCO can beused to extract population-level models describing the trends of accumulationof alterations in a cohort of cross-sectional samples, e.g., retrieved frompublicly available databases, and individual-level models that reveal theclonal evolutionary history in single cancer patients, when multiple samples,e.g., multiple biopsies or single-cell sequencing data, are available. Theresulting models can provide key hints in uncovering the evolutionarytrajectories of cancer, especially for precision medicine or personalizedtherapy.  Availability: TRONCO is released under the GPL license, it is hosted in theSoftware section at http://bimib.disco.unimib.it/ and archived also atbioconductor.org.  Contact: tronco@disco.unimib.it

TRONCO: an R package for the inference of cancer progression models from heterogeneous genomic data