Open AccessProteome analysis based on motif statistics
Author(s) -
Pierre Nicodème,
Tobias Doerks,
Martin Vingron
Publication year - 2002
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/18.suppl_2.s161
Subject(s) - motif (music) , proteome , computational biology , computer science , data science , biology , bioinformatics , physics , acoustics
Even for the amino acid motifs collected in the Prosite database there may be chance occurences as opposed to those occurences where the motif is involved in fold or function of a protein. With recent mathematical advances in assessing the significance of observing such a motif a particular number of times, we can now study the over- or under-representation of particular motifs in a complete genome and attempt to make functional deductions.