Open AccessProcessing and quality control of DNA array hybridization data
Author(s) -
Tim Beißbarth,
Kurt Fellenberg,
Benedikt Brors,
R. Arribas-Prat,
Judith M. Boer,
Nicole C. Hauser,
Marcel Scheideler,
Jörg D. Hoheisel,
G. Schütz,
Annemarie Poustka,
Martin Vingron
Publication year - 2000
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/16.11.1014
Subject(s) - computer science , computational biology , gene , dna , biology , dna–dna hybridization , data mining , genetics
The technology of hybridization to DNA arrays is used to obtain the expression levels of many different genes simultaneously. It enables searching for genes that are expressed specifically under certain conditions. However, the technology produces large amounts of data demanding computational methods for their analysis. It is necessary to find ways to compare data from different experiments and to consider the quality and reproducibility of the data.
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