Open AccessBrain Involvement in Myotonic Dystrophy Type 1: A Morphometric and Diffusion Tensor Imaging Study with Neuropsychological Correlation
Author(s) -
T. Cabada,
Marina Iridoy,
Ivonne Jericó,
Pablo Lecumberri,
Roberto Seijas,
Alberto Carreras Gargallo,
Marisol Gómez
Publication year - 2017
Publication title -
archives of clinical neuropsychology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.909
H-Index - 98
eISSN - 1873-5843
pISSN - 0887-6177
DOI - 10.1093/arclin/acx008
Subject(s) - myotonic dystrophy , neuropsychology , diffusion mri , correlation , psychology , neuroscience , medicine , audiology , magnetic resonance imaging , cognition , radiology , mathematics , geometry
Myotonic dystrophy type 1 (DM1), the most prevalent inherited neuromuscular disease in adults, is a genetic multisystem disorder with a well-established but not well-characterized cerebral involvement. The aim of this study was to evaluate the presence of white matter and gray matter abnormalities in DM1 patients and to investigate their relationship with neurocognitive dysfunction.
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