Open AccessNerve Growth Factor Protects Against Alcohol-Induced Neurotoxicity in PC12 Cells via PI3K/Akt/mTOR Pathway
Author(s) -
Liping Liu,
Tiedong Sun,
Feng Xin,
Wei Cui,
Jianquan Guo,
Jian Hu
Publication year - 2016
Publication title -
alcohol and alcoholism
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 0.747
H-Index - 99
eISSN - 1464-3502
pISSN - 0735-0414
DOI - 10.1093/alcalc/agw077
Subject(s) - pi3k/akt/mtor pathway , autophagy , ly294002 , protein kinase b , neurotoxicity , nerve growth factor , apoptosis , chemistry , neuroprotection , viability assay , programmed cell death , pharmacology , microbiology and biotechnology , biology , biochemistry , toxicity , receptor , organic chemistry
To study whether autophagy participates in the neuroprotective effect of nerve growth factor (NGF) on neurons treated with alcohol.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom