Molecular Genetics of Alcohol-Related Brain Damage
Author(s) -
Irene Guerrini,
A D Thomson,
Hugh Gurling
Publication year - 2008
Publication title -
alcohol and alcoholism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.747
H-Index - 99
eISSN - 1464-3502
pISSN - 0735-0414
DOI - 10.1093/alcalc/agn101
Subject(s) - thiamine , candidate gene , alcohol dependence , genetics , genetic predisposition , pathogenesis , medicine , gene , molecular genetics , biology , alcohol , biochemistry
In the scientific literature it has been repeatedly hypothesized that there is a heritable susceptibility to thiamine deficiency comparable to other hereditary metabolic disorders. The aim of this paper is to review the most recent knowledge on the genetic susceptibility to the development of alcohol-related Wernicke-Korsakoff syndrome (WKS).
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom