Transient Mild Cerebral Ischemia Significantly Deteriorated Cognitive Impairment in a Mouse Model of Alzheimer’s DiseaseviaAngiotensin AT1 Receptor
Author(s) -
Takashi Nakagawa,
Yu Hasegawa,
Ken Uekawa,
Satoru Senju,
Naomi Nakagata,
Kunihiko Matsui,
Shokei KimMitsuyama
Publication year - 2016
Publication title -
american journal of hypertension
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.009
H-Index - 136
eISSN - 1941-7225
pISSN - 0895-7061
DOI - 10.1093/ajh/hpw099
Subject(s) - medicine , olmesartan , ischemia , hippocampus , morris water navigation task , angiotensin ii , angiotensin ii receptor type 1 , anesthesia , blood pressure
Ischemic stroke is suggested to be potentially associated with cognitive impairment in Alzheimer's disease (AD). We hypothesized that cerebral ischemia deteriorates cognitive impairment in AD, through angiotensin II.
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