Open AccessHeme Oxygenase Improves Renal Function by Potentiating Podocyte-Associated Proteins in Nω-Nitro-l -Arginine-Methyl Ester (l -NAME)-Induced Hypertension
Author(s) -
Joseph Fomusi Ndisang,
Rajni Chibbar
Publication year - 2014
Publication title -
american journal of hypertension
Language(s) - English
Resource type - Journals
eISSN - 1941-7225
pISSN - 0895-7061
DOI - 10.1093/ajh/hpu240
Subject(s) - medicine , heme oxygenase , heme , arginine , pharmacology , renal function , podocyte , oxygenase , nitric oxide , nitro , kidney , endocrinology , biochemistry , enzyme , proteinuria , amino acid , chemistry , alkyl , organic chemistry
Although heme-oxygenase (HO) is cytoprotective, its effects on podocyte regulators like podocalyxin, podocin, CD2-associated protein (CD2AP) in renal dysfunction in N (ω)-nitro-l-arginine-methyl ester (l-NAME) hypertension are largely unclear.
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