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The GTPase Rac1 has been implicated in hypertension as a modulator of mineralocorticoid receptor activity. Our aim is to investigate the frequency of polymorphisms rs10951982 (intron 1, G&gt;A) and rs836478 (intron 3, T&gt;C) in the RAC1 gene and perform association studies with clinical and biochemical parameters in a Chilean pediatric cohort.

Polymorphisms in the RAC1 Gene Are Associated With Hypertension Risk Factors in a Chilean Pediatric Population