Open AccessLeft Ventricular Responses to Acute Changes in Late Systolic Pressure Augmentation in Older Adults
Author(s) -
Nancy K. Sweitzer,
Scott Hetzel,
Joseph H. Skalski,
M. Velez,
Karen Eggleston,
Gary F. Mitchell
Publication year - 2013
Publication title -
american journal of hypertension
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.009
H-Index - 136
eISSN - 1941-7225
pISSN - 0895-7061
DOI - 10.1093/ajh/hpt043
Subject(s) - medicine , afterload , preload , cardiology , stroke volume , hydralazine , ejection fraction , blood pressure , heart failure , brain natriuretic peptide , hemodynamics
Changes in the cardiovascular system with age may predispose older persons to development of heart failure with preserved ejection fraction. Vascular stiffening, aortic pressure augmentation, and ventricular-vascular coupling have been implicated. We explored the potential for acute reductions in late systolic pressure augmentation to impact left ventricular relaxation in older persons without heart failure.
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