A functional 19-base pair deletion polymorphism of dihydrofolate reductase (DHFR) and risk of breast cancer in multivitamin users | Zendy

Xinran Xu | Zendy; Marilie D. Gammon | Zendy; James G. Wetmur | Zendy; Manlong Rao | Zendy; Mia M. Gaudet | Zendy; Susan L. Teitelbaum | Zendy; Julie A. Britton | Zendy; Alfred I. Neugut | Zendy; Regina M. Santella | Zendy; Jia Chen | Zendy

Open Access

A functional 19-base pair deletion polymorphism of dihydrofolate reductase (DHFR) and risk of breast cancer in multivitamin users

Author(s) -

Xinran Xu,

Marilie D. Gammon,

James G. Wetmur,

Manlong Rao,

Mia M. Gaudet,

Susan L. Teitelbaum,

Julie A. Britton,

Alfred I. Neugut,

Regina M. Santella,

Jia Chen

Publication year - 2007

Publication title -

american journal of clinical nutrition

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.608

H-Index - 336

eISSN - 1938-3207

pISSN - 0002-9165

DOI - 10.1093/ajcn/85.4.1098

Subject(s) - genotype , dihydrofolate reductase , multivitamin , breast cancer , allele , biology , odds ratio , genetics , population , logistic regression , medicine , oncology , gynecology , endocrinology , cancer , gene , vitamin , environmental health

Dihydrofolate reductase (DHFR) converts dihydrofolate (DHF) into tetrahydrofolate (THF) and plays an essential role in cell metabolism and cellular growth. Folic acid from multivitamins needs to be reduced by DHFR before it participates in cellular reactions.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research

Address

John Eccles House
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom

About

About Careers Publisher Partners Contact Us Our institutional solutions Get Organisational Trial or Quote

Learn

FAQs Blog Terms of Use Privacy Policy

Download the Zendy App

Discover

Explore

Home ZAIA Blog