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We show that peroxisomes, but not lipid droplets, mitochondria, or preautophagosomes, hitchhike on early endosomes in Aspergillus nidulans hyphae using the linker protein PxdA. We discover a new regulator of hitchhiking, the DipA phosphatase, which is recruited to early endosomes by PxdA and is required for peroxisome, but not early endosome, motility.

PxdA interacts with the DipA phosphatase to regulate peroxisome hitchhiking on early endosomes