An MBoC Favorite: Regulation of the vitellogenin receptor during Drosophila melanogaster oogenesis

transmembrane vitellogenin receptor, Yolkless, the authors found transcripts and receptor protein are already present in very immature egg chambers, much earlier than yolk granules. The striking result was the altered subcellular localization of Yolkless when yolk storage begins; at this juncture, Yolkess exits the endoplasmic reticulum (ER) and traffics to the oolemma, permitting endocytic uptake and storage of yolk. Several