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This article came out in December 1995, while I was a postdoctoral fellow in Tim Mitchison’s lab at University of California, San Francisco, and shortly after I had discovered that kinesins could regulate microtubule dynamics. The review was extraordinarily helpful for me in that it provided a perspective that significantly clarified my thinking about the means by which microtubule dynamics could be harnessed to perform work. More generally, the years of knowledge of Inoue and Salmon are evident as you read this article, as well as their deep and brilliant thoughts about the problems at hand. While this article is approaching 20 years of age, I still recommend it to my graduate students, and in fact I think it is time for me to read it yet again.

An MBoC Favorite: Force generation by microtubule assembly/disassembly in mitosis and related movements