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To determine whether a nonprotein lipophilic carrier, 2-hydroxypropyl-beta-cyclodextrin (HP-beta-CD), can remove all-trans retinol from rod photoreceptor outer segments. All-trans retinol is generated in rod outer segments after light exposure. It is highly insoluble, and its efficient transport across extra- and intracellular aqueous space requires specialized carriers.

2-Hydroxypropyl-β-Cyclodextrin Removes All-TransRetinol from Frog Rod Photoreceptors in a Concentration-Dependent Manner