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There are methodological ambiguities in the literature on mesh refinement analysis for computational fluid dynamics (CFD) modeling of physiologically realistic airflow dynamics and particle transport in the human sinonasal cavity. To investigate grid independence in discretization of the (sino)nasal geometry, researchers have considered CFD variables such as pressure drop, velocity profile, wall shear, airflow, and particle deposition fractions. Standardization in nasal geometry is also lacking: unilateral or bilateral nasal cavities with and without paranasal sinuses have been used. These methodological variants have led to inconsistencies in establishing grid-independent mesh densities. The aim of this study is to provide important insight in the role of mesh refinement analysis on airflow and particle deposition in sinonasal airway modeling.

Influence of Mesh Density on Airflow and Particle Deposition in Sinonasal Airway Modeling