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Janus kinase 1 (JAK1) is a key member in the interferon (IFN) signaling pathway. Recent studies suggested single-nucleotide polymorphisms (SNPs) in IFN pathway genes are associated with outcomes of hepatitis B virus (HBV) infection and response to IFNα therapy. The aim of the study is to investigate whether SNPs in JAK1 were associated with outcomes of HBV infection and response to IFNα therapy.

genetic testing and molecular biomarkers

<i>JAK1</i> Gene Polymorphisms Are Associated with the Outcomes of Hepatitis B Virus Infection, but Not with α Interferon Therapy Response in a Han Chinese Population

JAK1 Gene Polymorphisms Are Associated with the Outcomes of Hepatitis B Virus Infection, but Not with α Interferon Therapy Response in a Han Chinese Population