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Shiga toxin-producing Escherichia coli (STEC) are an important cause of foodborne disease, yet global estimates of disease burden do not exist. Our objective was to estimate the global annual number of illnesses due to pathogenic STEC, and resultant hemolytic uremic syndrome (HUS), end-stage renal disease (ESRD), and death.

Global Incidence of Human Shiga Toxin–ProducingEscherichia coliInfections and Deaths: A Systematic Review and Knowledge Synthesis