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Sometimes, I think that trying to be an authentic clinician-scientist who straddles successfully the majestic fields of scientific research and clinical medicine is well-nigh impossible. The inherent danger of such an endeavor is that by trying to be good at both laboratory research and managing sick patients, one ends up by failing to do either well so that basic scientists are skeptical about your scientific knowledge and ability while your clinical colleagues do not regard you as a top-notch clinician, with both groups viewing you with not a little suspicion. No one can guarantee success in such a combined role but for sure I can think of three things that help a lot, indeed are critical: obtaining a first class training in both research work and clinical medicine, genuine enthusiasm, indeed passion, for both finding things out through research and looking after patients, and, crucially, good mentorship. While I am innately very self-critical (and with good reason!), overall I consider myself as having been quite fortunate in having experienced all three of these, and, of course, the last, indeed essential, ingredient to becoming a successful clinician-scientist is a smattering of good luck, which no-one can guarantee. But at least it is possible I believe to create a career background and attitude that is conducive to good choices, the avoidance of potential disasters (which unfortunately I have seen on occasion first hand) and consistent with the often quoted notion that “chance favors the prepared mind.” Avoidance of bad luck, if at all possible, may be just as, if not more, important as experiencing good luck. And it goes without saying that you really have to enjoy being this kind of person in such a dual role.

My Life as a Clinician-Scientist: Trying to Bridge the Perceived Gap Between Medicine and Science