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Radioimmunotherapy of cancer with radiolabeled antibodies has shown promise. We evaluated an anti-CD25 monoclonal Antibody, 7G7/B6, armed with (90)Y as a potential radioimmunotherapeutic agent for CD25-expressing lymphomas.

cancer biotherapy and radiopharmaceuticals

Preclinical Evaluation of an Anti-CD25 Monoclonal Antibody, 7G7/B6, Armed with the β-Emitter, Yttrium-90, as a Radioimmunotherapeutic Agent for Treating Lymphoma