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The mechanisms underlying numerous biological roles of hydrogen sulfide (H2S) remain largely unknown. We have previously reported an inhibitory role of H2S in the L-type calcium channels in cardiomyocytes. This prompts us to examine the mechanisms underlying the potential regulation of H2S on the ion channels.

antioxidants and redox signaling

Hydrogen Sulfide Targets the Cys320/Cys529 Motif in Kv4.2 to Inhibit the <i>I</i><sub>to</sub> Potassium Channels in Cardiomyocytes and Regularizes Fatal Arrhythmia in Myocardial Infarction

Hydrogen Sulfide Targets the Cys320/Cys529 Motif in Kv4.2 to Inhibit the Ito Potassium Channels in Cardiomyocytes and Regularizes Fatal Arrhythmia in Myocardial Infarction

Hydrogen Sulfide Targets the Cys320/Cys529 Motif in Kv4.2 to Inhibit the I_to Potassium Channels in Cardiomyocytes and Regularizes Fatal Arrhythmia in Myocardial Infarction