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Oxidative stress and damage are well-established components of neurodegenerative diseases, contributing to neuronal death during disease progression. Here, we consider key K(+) channels as target proteins that can undergo oxidative modulation, describe what is understood about how this influences disease progression, and consider regulation of these channels by gasotransmitters as a means of cellular protection.

Oxidative Modulation of K+ Channels in the Central Nervous System in Neurodegenerative Diseases and Aging

Oxidative Modulation of K⁺ Channels in the Central Nervous System in Neurodegenerative Diseases and Aging