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Hydrogen sulfide (H2S), once associated with rotten eggs and sewers, is now recognized as a gasotransmitter that is synthesized in vivo in a regulated fashion. This ancient gaseous molecule has been retained throughout evolution to perform various roles in different life forms. H2S modulates important signaling functions in diverse cellular processes ranging from regulation of blood pressure to redox homeostasis.

Modes of Physiologic H2S Signaling in the Brain and Peripheral Tissues

Modes of Physiologic H₂S Signaling in the Brain and Peripheral Tissues