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Pancreatic cancer (PC) is the most aggressive malignant disease, ranking as the fourth most leading cause of cancer-related death among men and women in the United States. In this study, we provide evidence of chemotherapeutic effects of α-mangostin, a dietary antioxidant isolated from the pericarp of Garcinia mangostana L. against human PC.

antioxidants and redox signaling

α-Mangostin: A Dietary Antioxidant Derived from the Pericarp of <i>Garcinia mangostana</i> L. Inhibits Pancreatic Tumor Growth in Xenograft Mouse Model

α-Mangostin: A Dietary Antioxidant Derived from the Pericarp of Garcinia mangostana L. Inhibits Pancreatic Tumor Growth in Xenograft Mouse Model