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Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis (TB), can persist in a latent state for decades without causing overt disease. Since latent Mtb is refractory to current antimycobacterial drugs, the discovery and characterization of the biological mechanisms controlling the entry, maintenance, and emergence from latent infection is critical to the development of novel clinical therapies.

Mycobacterium tuberculosisWhiB3: A Novel Iron–Sulfur Cluster Protein That Regulates Redox Homeostasis and Virulence