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Objective: Acupressure applied on the Extra-1 ( Yintang ) point decreases bispectral index (BIS) values and stress in healthy volunteers. The current authors hypothesized that acupressure and/or acupuncture could alter regional cerebral oxygenation as expressed by middle cerebral-artery velocity. This study was conducted to test that hypothesis. Materials and Methods: After giving written informed consent, healthy volunteers received, randomly, (1) acupressure on the Extra-1 ( Yintang ) point, (2) acupressure on a sham point lying 2 cm over the lateral end of the right eyebrow, (3) no acupressure, or (4) modified manual acupuncture on the Extra-1 ( Yintang ) point. Each intervention lasted 10 minutes, except for acupuncture, which lasted for 20 minutes. The flow velocity of the left middle cerebral artery-as expressed by the Pulsatility Index (PI), heart rate (HR), and hemoglobin oxygen saturation (SpO 2 )-was recorded before each intervention, every 2 minutes during the intervention, and 10 and 70 minutes after the end of the intervention. A 2-MHz hand-held probe of a transcranial Doppler system (Companion II Micro TCD Nikolet Biomedical Inc., Madison, WI) was used to isolate the left middle cerebral artery via a transtemporal approach. Results: There was no difference among the four interventions at any timepoint in PI ( P  = 0.431; F  = 0.929), HR ( P  = 0.948; F  = 0.121), and SpO 2 ( P  = 0.708; F  = 0.465), as well as in systolic arterial pressure ( P  = 0.857; F  = 0.255) or diastolic arterial pressure ( P  = 0.991; F  = 0.036). Conclusions: There were no changes in PI measurements when acupuncture or acupressure was applied on the Extra-1 ( Yintang ) point once and for a limited time duration.

medical acupuncture

Acupuncture and Acupressure Applied on the Extra-1 (<i>Yintang</i>) Acupoint in Healthy Volunteers Do Not Affect Regional Cerebral Blood Flow as Assessed by the Pulsatility Index: A Cohort Observational Study

Acupuncture and Acupressure Applied on the Extra-1 (Yintang) Acupoint in Healthy Volunteers Do Not Affect Regional Cerebral Blood Flow as Assessed by the Pulsatility Index: A Cohort Observational Study