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The refrigeration, air-conditioning and heat pumping industries are essential sectors of the world economy. The list of the major synthetic refrigerants characterized by the non-flammability, low toxicity, good thermophysical properties and stability are reviewed. The HCFCs and fully halogenated CFCs refrigerants are responsible for the destruction of stratospheric ozone. The paper details the effects of two allergens – the global climate change and the depletion of stratospheric ozone due to chlorofluorocarbons, hydrochlorofluorocarbons and hydrofluorocarbons. This situation has been estimated as sufficient to cause alarm. The urgent task today is to develop harmless refrigerants with zero ozone depletion potential and a minimal greenhouse effect potential.

Global allergens and refrigeration alarmism