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Hyperglicemia is a condition in which blood glucose levels. The condition of chronies hyperglycemia result in creased free radical production resulting in oxcidative stress. Oxidatived stress is one component in the mechanism of damage cell in pangcreas hyperglycemia Wistar rat. This Research true experimental with The Randomized Pre and Posttest Control Group Design. Oxidative stress be demonstrated by increasing 8-hidroxi-2-dihidroxiguanosin (8-OHdG) levels. Antioxidant compound active phenol in brassica rapa L. Phenol is group contained in medical plants can reduce the occurrence of hyperglycemia. This study to determinethe effect of giving brassica rapa L ethanol extract (Brassica rapa L) in decreasing reducing 8- OHdG levels in hyperglycemics Wistar rats. Wistar rats that have experienced hyperglycemia were divided into 6 groups. Po (Normal groups). P1( positive control with given glibenclamide). and P3. P4. P5 (treatment was given orally with green mustard of 10 mg / kg BW; 15 mg/kg BW ; 20mg/kg BW) can decreasing 8-OHdG (8-Hydroxi-2-dioxyguanosin) . The result of treatmen ethanol extract brassica rapa L showed P0: 2.440 ng/dL. P1:7.482 ng/dL; P2 :2.772 ng/dL; P3:5.158 ng/dL: P4: 2.304 ng/dL . The content of phenol groups in capturing of neutralizing the radical scavenging in hyperglycemic Wistar rats. One Way Anova analysis and Post Hoc Study showed that ethanol extract brassica rapa L extract doses 5.0 mg/kgBW was able to significantly ( P⩽ 0.05) can decreasing damage cell in hyperglycemic Wistar rats

Green Mustard Ethanol Extract (Brassica Rapa L.) Leaf Can Cell Damage (8-Hydroxy-2-Dioxiguanosine) In The Wistar Rat Hyperglicemic