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An actual task is to project industrial purposes cyber and physical systems interaction technologies in the Industry 4.0 smart factories. Three cyber and physical systems interaction options are described (mechanical, informative and man and machine) which are applied in the item designing components manufacturing technological process. A scheme of system projection route is proposed for the cyber and physical interaction technologies. A scheme of system projection route is proposed for digital production cloud resources (services and applications) which are applied to realize automatic informative interaction for cyber and physical systems digital twins.

Designing technologies for the interaction of cyber-physical systems in smart factories of the Industry 4.0