English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

We present a simple two-state model to understand the size-dependentendocytosis of nanoparticles. Using this model, we elucidate the relevantenergy terms required to understand the size-dependent uptake mechanism andverify it by correctly predicting the behavior at large and small particlesizes. In the absence of interactions between the nanoparticles we observe anasymmetric distribution of sizes with maximum uptake at intermediate sizes anda minimum size cut-off below which there can be no endocytosis. Including theeffect of interactions in our model has remarkable effects on the uptakecharacteristics. Attractive interactions shift the minimum size cut-off andincrease the optimal uptake while repulsive interactions make the distributionmore symmetric lowering the optimal uptake.

Effect of interactions on the cellular uptake of nanoparticles